The main pharmaco-therapeutic effects: inhibits bone resorption, acts as a powerful inhibitor of bone resorption, which are osteoblasts, thus does not directly impact on the development of bone. Drugs affecting bone on purpose and mineralization. Contraindications to use drugs: lesion of esophagus, which slows its emptying (narrowing or achalasia), inability to stand or sit upright less than 30 min, hypersensitivity to drug; hypocalcemia. on purpose of production of drugs: granules for the preparation of suspensions of 2 g (100 mg) in bags, tab. The main pharmaco-therapeutic effect: a dual mechanism of action and intended for the treatment of postmenopausal osteoporosis to reduce the risk of fractures of cervical vertebral bodies and hips, increases bone formation in bone tissue culture, propagation and predecessors osteoblasts and Lymphadenopathy synthesis in bone cell culture, reduces bone resorption by decrease on purpose differentiation and reduced their activity rezorbtsiynoyi; dual mechanism of action leads to rebalancing of metabolism in here tissue in favor of osteogenesis; increases trabecular bone mass, their number and thickness of the trabecula, resulting in increased bone strength; strontium in bone tissue is mainly adsorbed on surface of apatite crystals and only a small number replaces calcium in apatite crystals in the newly formed bone tissue. Pharmacotherapeutic group: M05VA04 - a means of influencing the structure and mineralization of bone. Method of production of drugs: Mr injection, 10 mg / 0,5 ml 0,5 ml, 20 mg / 0,5 ml 0,5 ml, 50 mg / 0,5 ml 0,5 ml. Contraindications to the use of drugs: violation of haematopoietic process, renal impairment, severe liver damage, active pulmonary tuberculosis, common diseases of connective tissue (connective tissue disease such as lupus dysseminovanyy, total nodular arteritis, skleroderma, on purpose hypersensitivity on purpose multiple substances ( polialerhiyi), allergies to heavy metals and salts of gold, gold contact allergy, inflammation of the mucous membrane of the colon (ulcerative colitis), diabetes with complications, pregnancy, lactation. Side effects on purpose complications in the use of drugs: hypersensitivity reactions, including urticaria and rarely angioedema, early treatment - myalgia, malaise, fever, Outpatient Visit hypocalcemia, abdominal pain, dyspepsia, esophageal ulcer, dysphagia, bloating, on purpose , vomiting, esophagitis, esophageal erosions and oropharynx, stomach and duodenum ulcers, rash (sometimes with photosensitization), itching, severe skin reactions, including c-m Stevens-Johnson and toxic epidermal nekroli, uveitis, or skleryt episkleryt. Dosing and Administration of drugs: the recommended daily dose of 2 g / day, before applying to dissolve in on purpose glass of water is advised to take before bedtime, preferably not on purpose Fasting Blood Sugar c / 2 hours after meals, designed for long use. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action, acts as an inhibitor of prostaglandin Bronchoalveolar Lavage enzyme cyclooxygenase.
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