The main pharmaco-therapeutic effects: inhibits bone resorption, acts as a  powerful inhibitor of bone resorption, which are osteoblasts, thus does not  directly impact on the development of bone. Drugs affecting bone on purpose and  mineralization. Contraindications to use drugs: lesion of esophagus, which slows  its emptying (narrowing or achalasia), inability to stand or sit upright less  than 30 min, hypersensitivity to drug; hypocalcemia. on purpose of production of  drugs: granules for the preparation of suspensions of 2 g (100 mg) in bags, tab.  The main pharmaco-therapeutic effect: a dual mechanism of action and intended  for the treatment of postmenopausal osteoporosis to reduce the risk of fractures  of cervical vertebral bodies and hips, increases bone formation in bone tissue  culture, propagation and predecessors osteoblasts and Lymphadenopathy  synthesis in bone cell culture, reduces bone resorption by decrease on purpose  differentiation and reduced their activity rezorbtsiynoyi; dual mechanism of  action leads to rebalancing of metabolism in here  tissue in favor of osteogenesis; increases trabecular bone mass, their number  and thickness of the trabecula, resulting in increased bone strength; strontium  in bone tissue is mainly adsorbed on surface of apatite crystals and only a  small number replaces calcium in apatite crystals in the newly formed bone  tissue. Pharmacotherapeutic group: M05VA04 - a means of influencing the  structure and mineralization of bone. Method of production of drugs: Mr  injection, 10 mg / 0,5 ml 0,5 ml, 20 mg / 0,5 ml 0,5 ml, 50 mg / 0,5 ml 0,5 ml.  Contraindications to the use of drugs: violation of haematopoietic process,  renal impairment, severe liver damage, active pulmonary tuberculosis, common  diseases of connective tissue (connective tissue disease such as lupus  dysseminovanyy, total nodular arteritis, skleroderma, on purpose  hypersensitivity on purpose multiple substances ( polialerhiyi), allergies to  heavy metals and salts of gold, gold contact allergy, inflammation of the mucous  membrane of the colon (ulcerative colitis), diabetes with complications,  pregnancy, lactation. Side effects on purpose complications in the use of drugs:  hypersensitivity reactions, including urticaria and rarely angioedema, early  treatment - myalgia, malaise, fever, Outpatient Visit  hypocalcemia, abdominal pain, dyspepsia, esophageal ulcer, dysphagia, bloating,  on purpose , vomiting, esophagitis, esophageal erosions and oropharynx, stomach  and duodenum ulcers, rash (sometimes with photosensitization), itching, severe  skin reactions, including c-m Stevens-Johnson and toxic epidermal nekroli,  uveitis, or skleryt episkleryt. Dosing and Administration of drugs: the  recommended daily dose of 2 g / day, before applying to dissolve in on purpose  glass of water is advised to take before bedtime, preferably not on purpose Fasting Blood Sugar c / 2 hours after  meals, designed for long use. The main pharmaco-therapeutic effects:  anti-inflammatory, analgesic, antipyretic action, acts as an inhibitor of  prostaglandin Bronchoalveolar  Lavage enzyme cyclooxygenase. 
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